| Accession Number | DEG10510002 |
| Gene name | dnaN |
| Gene Ref | Protein_ID: AAG03392.1 |
| RefSeq | NC_002516 |
| Function Class | - |
| Description | DNA polymerase III, beta chain |
| Uniprot accession | - |
| Organism | Pseudomonas aeruginosa PAO1 |
| Condition | LB agar, MOPS-pyruvate agar and Cystic fibrosis sputum agar |
| Uniprot accession | Q9I7C4 |
| Operon ID in DOOR database | 12029 |
| COG | COG0592L |
| Location | 2056..3159(+); leading strand |
| Reference | Lee, S. A., Gallagher, L. A., Thongdee, M., Staudinger, B. J., Lippman, S., Singh, P. K., & Manoil, C. (2015). General and condition-specific essential functions of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences, 112(16), 5189-5194. |
| Nucleotide sequence |
Length: 1104 nt ATGCATTTCACCATTCAACGCGAAGCCCTGTTGAAACCGCTGCAACTGGTCGCCGGCGTCGTGGAACGCCGCCAGACATTGCCGGTTCTCTCCAACGTCCTGCTGGTGGTCGAAGGCCAGCAACTGTCGCTGACCGGCACCGACCTCGAAGTCGAGCTGGTTGGTCGCGTGGTACTGGAAGATGCCGCCGAACCCGGCGAGATCACCGTACCGGCGCGCAAGCTGATGGACATCTGCAAGAGCCTGCCGAACGACGTGCTGATCGACATCCGTGTCGAAGAGCAGAAACTTCTGGTGAAGGCCGGGCGTAGCCGCTTCACCCTGTCCACCCTGCCGGCCAACGATTTCCCCACCGTAGAGGAAGGTCCCGGCTCGCTGAACTTCAGCATTGCCCAGAGCAAGCTGCGTCGCCTGATCGACCGCACCAGCTTCGCCATGGCCCAGCAGGACGTGCGTTACTACCTCAACGGCATGCTGCTGGAAGTGAACGGCGGCACCCTGCGCTCCGTCGCCACCGACGGCCACCGACTGGCCATGTGCTCGCTGGATGCGCAGATCCCGTCGCAGGACCGCCACCAGGTGATCGTGCCGCGCAAAGGCATCCTCGAACTGGCTCGTCTGCTCACCGAGCAGGACGGCGAAGTCGGCATCGTCCTGGGCCAGCACCATATCCGTGCCACCACTGGCGAATTCACCTTCACTTCGAAGCTGGTGGACGGCAAGTTCCCGGACTACGAGCGTGTACTGCCGCGCGGTGGCGACAAGCTGGTGGTCGGTGACCGCCAGCAACTGCGCGAAGCCTTCAGCCGTACCGCGATCCTCTCCAACGAGAAGTACCGCGGCATTCGCCTGCAGCTTTCCAACGGTTTGCTGAAAATCCAGGCGAACAACCCGGAGCAGGAAGAGGCCGAGGAAGAAGTGCAGGTCGAGTACAACGGCGGCAACCTGGAGATAGGCTTCAACGTCAGTTACCTGCTCGACGTGCTGGGTGTGATCGGTACCGAGCAGGTCCGCTTCATCCTTTCCGATTCCAACAGCAGCGCCCTGGTCCACGAGGCCGACAATGACGATTCTGCCTATGTCGTCATGCCGATGCGCCTCTAA |
| Amino acid sequence |
Length: 367 aa MHFTIQREALLKPLQLVAGVVERRQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLEDAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVEEGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMCSLDAQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDGKFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQEEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDSAYVVMPMRL |
| Annotation By eggNOG | |
| eggNOG otrhologs | 287.DR97_2951 |
| EC number | 2.7.7.7 |
| GO annotation | GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 |
| KEGG_ko | K02338 |
| KEGG_Pathway | ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 |
| eggNOG OGs | 1MVD9@1224,1RMNP@1236,1YDYY@136841,COG0592@1,COG0592@2 |
| eggNOG free text description | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria |