| Accession Number | DEG10510008 |
| Gene name | def |
| Gene Ref | Protein_ID: AAG03409.1 |
| RefSeq | NC_002516 |
| Function Class | - |
| Description | polypeptide deformylase |
| Uniprot accession | - |
| Organism | Pseudomonas aeruginosa PAO1 |
| Condition | LB agar, MOPS-pyruvate agar and Cystic fibrosis sputum agar |
| Uniprot accession | Q9I7A8 |
| Operon ID in DOOR database | 1397346 |
| COG | COG0242J |
| Location | 21067..21573(-); lagging strand |
| Reference | Lee, S. A., Gallagher, L. A., Thongdee, M., Staudinger, B. J., Lippman, S., Singh, P. K., & Manoil, C. (2015). General and condition-specific essential functions of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences, 112(16), 5189-5194. |
| Nucleotide sequence |
Length: 507 nt ATGGCCATCCTGAACATTCTCGAATTCCCCGATCCGCGCCTGCGGACCATCGCCAAACCGGTGGAGGTGGTCGACGACGCGGTGCGCCAGCTGATCGACGACATGTTCGAAACCATGTACGAAGCCCCGGGCATCGGCCTCGCCGCGACCCAGGTGAACGTGCACAAGCGCATCGTGGTCATGGACCTCAGCGAAGACAAGTCCGAGCCGAGGGTATTCATCAACCCCGAGTTCGAACCGCTGACCGAGGATATGGACCAGTACCAGGAAGGCTGCCTGTCGGTACCCGGCTTCTACGAGAACGTGGACCGACCGCAGAAGGTCCGGATCAAGGCCCTCGACCGCGATGGCAACCCCTTCGAGGAAGTCGCCGAAGGCCTGCTGGCGGTATGCATCCAGCACGAATGCGACCACCTCAACGGCAAGCTGTTCGTCGACTACCTGTCCACCCTCAAGCGCGACCGCATCCGCAAGAAGCTGGAAAAGCAGCATCGACAGCAGGCGTGA |
| Amino acid sequence |
Length: 168 aa MAILNILEFPDPRLRTIAKPVEVVDDAVRQLIDDMFETMYEAPGIGLAATQVNVHKRIVVMDLSEDKSEPRVFINPEFEPLTEDMDQYQEGCLSVPGFYENVDRPQKVRIKALDRDGNPFEEVAEGLLAVCIQHECDHLNGKLFVDYLSTLKRDRIRKKLEKQHRQQA |
| Annotation By eggNOG | |
| eggNOG otrhologs | 287.DR97_2972 |
| EC number | 3.5.1.88 |
| GO annotation | GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 |
| KEGG_ko | K01462 |
| KEGG_Pathway | |
| eggNOG OGs | 1RA2P@1224,1S247@1236,1YDAH@136841,COG0242@1,COG0242@2 |
| eggNOG free text description | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions |