| Accession Number | DEG10510035 |
| Gene name | metF |
| Gene Ref | Protein_ID: AAG03819.1 |
| RefSeq | NC_002516 |
| Function Class | - |
| Description | 5,10-methylenetetrahydrofolate reductase |
| Uniprot accession | - |
| Organism | Pseudomonas aeruginosa PAO1 |
| Condition | LB agar, MOPS-pyruvate agar and Cystic fibrosis sputum agar |
| Uniprot accession | Q9I687 |
| Operon ID in DOOR database | 12120 |
| COG | COG0685E |
| Location | 481196..482068(-); lagging strand |
| Reference | Lee, S. A., Gallagher, L. A., Thongdee, M., Staudinger, B. J., Lippman, S., Singh, P. K., & Manoil, C. (2015). General and condition-specific essential functions of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences, 112(16), 5189-5194. |
| Nucleotide sequence |
Length: 873 nt GTGGTCGCGTCCAAGGAACCGATCATGAGTCAGAGCGAACGCCGTTTCAGCTTCGAGTTCTTCCCGGCGAAGACCGAGGCCGGCCATGAAAAGCTGTTGGCCACCGCCCGCAACCTGGCGGGCTACAAGCCCGACTTCTTCTCCTGCACCTACGGCGCCGGCGGATCCACCCGCGACCGCACGTTGAGTACCGTGCTGCAACTGGACGGCGAGGTGAAGGTGCCGACCGCGCCGCACCTGTCCTGTGTCGGCGACTCGAAAGCCGAGTTGCGCGAACTGCTCGGCCGCTACCGCGAGGCCGGCATCCGCCGCATCGTCGCCCTGCGCGGCGACCTGCCGTCGGGCATGGGCATGGCCAGCGGCGAACTGCGCTACGCCAACGAACTGGTGGACTTCATCCGCACCGAGACCGGCGACCACTTCCACATCGAGGTCGCCGCCTATCCGGAGGTCCACCCCCAGGCGCGCAGCTTCGAGGATGACCTGGCGAACTTCGTGCGCAAGGTGAAGGCCGGCGCCAGCAGCGCCATCACCCAGTACTTCTTCAACGCCGATGCCTATTTCTACTTCGTCGAGCGGGTCGCCAAGCTCGGCGTGGACATCCCGGTGGTCCCCGGCATCATGCCGATCACCAACTACTCCAAGCTGGCGCGCTTCTCCGACGCCTGCGGCGCCGAACTGCCGCGCTGGATCCGCAAGCAACTGGAAGCCTACGGCGACGACAGCCGCAGCATCCAGGCCTTCGGCGAGCAGGTCATCAGCGAGATGTGCGAACGCCTGCTGGAGGGCGGCGCACCGGGACTGCATTTCTATACTTTGAACCAGGCCGATCCGAGCCTGGCGATCTGGAAGAATCTCCAGCTGCCACGCTGA |
| Amino acid sequence |
Length: 290 aa MVASKEPIMSQSERRFSFEFFPAKTEAGHEKLLATARNLAGYKPDFFSCTYGAGGSTRDRTLSTVLQLDGEVKVPTAPHLSCVGDSKAELRELLGRYREAGIRRIVALRGDLPSGMGMASGELRYANELVDFIRTETGDHFHIEVAAYPEVHPQARSFEDDLANFVRKVKAGASSAITQYFFNADAYFYFVERVAKLGVDIPVVPGIMPITNYSKLARFSDACGAELPRWIRKQLEAYGDDSRSIQAFGEQVISEMCERLLEGGAPGLHFYTLNQADPSLAIWKNLQLPR |
| Annotation By eggNOG | |
| eggNOG otrhologs | 287.DR97_3398 |
| EC number | 1.5.1.20 |
| GO annotation | GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 |
| KEGG_ko | K00297 |
| KEGG_Pathway | ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 |
| eggNOG OGs | 1MUC9@1224,1RMXS@1236,1YDSQ@136841,COG0685@1,COG0685@2 |
| eggNOG free text description | Methylenetetrahydrofolate reductase |